This may be a bit more appropriate for the "Off Topic" forum, but I thought it might provoke some Frasier discussion.
In Desperately Seeking Closure, Sam breaks up with Frasier and says that sometimes, things just end. I've always had a hard time believing that, and I've always been on Frasier's side when he attempts to get the others to list his flaws. They'd been in a relationship for two months; that's not a long time, but Frasier didn't do anything that would put Sam off, and I don't think it's possible to stop being attracted to someone overnight. And by the end of the episode, we find out that Sam was having commitment problems, therefore there was a reason she broke up with him.
(Also, I found it a little strange that Niles said, "The relationship ended, that's what happened." He's a psychiatrist, he believes that there are no accidents, so imo it would be more suitable if he'd said, "Maybe it wasn't anything you did or said, maybe she has some issues.")
Anyway, I felt it's one of the situations in Frasier that translates well into real life. Have you ever been in a similar situation? Ever broken up with someone because things "just ended"?